Momordica charantia, commonly known as bitter melon, is a climber belonging to the Cucurbitaceae family. Bitter melon has been used in the traditional medicine of China, India, and Sri Lanka for a long time to treat a variety of diseases. The anti-obesity benefits of bitter melon’s numerous bioactive components have been shown at the cellular and organismal levels. Proteins, triterpenoids, saponins, phenolics, and conjugated linolenic acids were among the key bioactive components that showed anti-obesity activity in bitter melon. Their strategies included fat synthesis suppression, glucose utilization enhancement, and activation of auxiliary lipid-lowering activities. Overall, the study establishes the therapeutic potential of bitter melon.
Fan, M., Kim, E.-K., Choi, Y.-J., Tang, Y., & Moon, S.-H. (2019). The role of momordica charantia in resisting obesity. International Journal of Environmental Research and Public Health, 16(18). https://doi.org/10.3390/ijerph16183251